Navigating green synthesized metal-based nanoparticles as anti-inflammatory agent - Comprehensive review

Area of Science:

• Nanomaterials Science
• Biomedical Engineering
• Pharmacology

Background:

• Nanoparticles (NPs) have diverse applications, especially in pharmaceutical and biomedical fields.
• Traditional physical and chemical methods for NP synthesis exist.
• Inflammation is a defense mechanism that can become chronic and harmful.

Purpose of the Study:

• To review advancements in green synthesis of silver, zinc, and copper NPs.
• To explore the potential of biosynthesized NPs as therapeutic agents for inflammatory diseases.
• To discuss factors influencing NP properties for effective nanomedicine formulation.

Main Methods:

• Focus on green synthesis approaches for metal and metal oxide NPs.
• Review of eco-friendly methods for NP generation.
• Analysis of NP properties relevant to anti-inflammatory applications.

Main Results:

• Green synthesis provides simple and eco-friendly routes for NP production.
• Biosynthesized NPs demonstrate potential as alternative therapeutic agents.
• NP size influences their efficacy in mitigating inflammatory conditions.

Conclusions:

• Green synthesized metal NPs offer promising therapeutic strategies for inflammatory diseases.
• Understanding NP physicochemical properties, toxicity, and biocompatibility is crucial for nanomedicine development.
• Biosynthesized NPs represent a viable option for novel anti-inflammatory drug formulations.