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Human Egg Maturity Assessment and Its Clinical Application

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[Research progress in biological activities and oocyte aging-regulating effect of EGCG]

Weiying Zhang¹, Huizhu Zhang^1,2, Yujun Li¹

¹College of Animal & Veterinary Sciences, Southwest Minzu University, Chengdu 610041, Sichuan, China.

Sheng Wu Gong Cheng Xue Bao = Chinese Journal of Biotechnology

|December 26, 2024

Abstract:

Epigallocatechin gallate (EGCG), the predominant polyphenol in green tea, exerts a spectrum of physiological activities, including antioxidant, anticancer, and anti-inflammatory effects. Emerging research underscores the significance of EGCG in modulating oocyte aging. EGCG can enhance antioxidant defenses, improve mitochondrial functions, and inhibit apoptotic pathways, thereby retarding the aging of oocytes. This review delineates the main molecular features of EGCG and expounds its regulatory mechanisms concerning oocyte aging, enriching the knowledge on the role of EGCG in the amelioration of oocyte aging.

Keywords:

antioxidant epigallocatechin gallate (EGCG)oocyte aging oxidative stress

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