COVID-19 Pneumonia Diagnosed by Bronchoalveolar Lavage Fluid, With CD4 T-cell Depletion Contributing to Prolonged Infection: Two Case Reports
Related Concept Videos
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
• Pleurisy: indicates the inflammation of the pleura, which causes chest pain and discomfort.
• Pleural Effusion: indicates fluid buildup in the pleural space.
• Atelectasis: Partial collapse of a lung lobe due to mucus blockage or external compression.
• Bacteremia: Bacterial infection entering the bloodstream, commonly seen with...
The pathophysiology of pneumonia involves the following steps:
• Inhalation of Infectious Agents: Pneumonia typically begins when pathogenic organisms (bacteria, viruses, fungi) are inhaled or aspirated into the lower respiratory tract.
• Overcoming Lung Defenses: Ideally, the respiratory tract has defense mechanisms like mucociliary clearance and cough reflex to prevent the establishment of pathogenic organisms. If these defenses are compromised, or the pathogen is highly...
Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
• For...
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
• Inhalation of Irritants: Inhaling irritants, especially cigarette smoke, are primary causes of inflammation in COPD. Other irritants can include...

