Fasting Glycemia, Glycosylated Hemoglobin and Malnutrition Inflammation Are Associated With Sarcopenia in Older People With Chronic Kidney Disease Undergoing Hemodialysis Treatment: A Cross-Sectional Study
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View abstract on PubMed
Summary
This summary is machine-generated.Sarcopenia is common in hemodialysis patients with chronic kidney disease (CKD). Higher fasting blood sugar is linked to increased sarcopenia risk in these older adults.
Area Of Science
- Nephrology
- Geriatrics
- Metabolism
Background
- Conflicting data exist on sarcopenia's association with clinical disorders in hemodialysis patients.
- Sarcopenia is a significant concern in older adults with chronic kidney disease (CKD).
Purpose Of The Study
- To investigate the link between sarcopenia and systemic inflammation, fasting glucose, and quality of life in elderly hemodialysis patients.
- Determine predictors of sarcopenia in this population.
Main Methods
- Cross-sectional study involving individuals over 60 with stage 5 CKD on hemodialysis.
- Sarcopenia assessed using European Working Group criteria.
- Clinical data included BMI, comorbidities, malnutrition-inflammation score, quality of life, glycemic markers, and blood parameters.
Main Results
- Prevalence of sarcopenia was 56.5% among 23 participants.
- Sarcopenic patients had higher fasting glucose, HbA1c, and malnutrition-inflammation scores.
- Significant correlations found between sarcopenia and fasting glucose (r=0.48), HbA1c (r=0.44), and malnutrition-inflammation (r=0.46).
Conclusions
- Sarcopenia is associated with elevated fasting glucose, HbA1c, and malnutrition-inflammation in older hemodialysis patients.
- Fasting glucose emerged as a significant predictor of sarcopenia.
- Further research is needed on glycemic control's impact on sarcopenia in older CKD patients.
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