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Quantitative Electroencephalography Biomarkers in Patients With Anti-N-methyl-D-aspartate Receptor Encephalitis: A

César Alejandro David Cancino1, Carlos Trenado2, Peter W Kaplan3

  • 1Clinical Neurophysiology Department, National Institute of Neurology and Neurosurgery, Mexico City, Mexico.

Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society
|December 26, 2024
PubMed
Abstract

Keywords:
Autoimmune encephalitis anti-NMDAREEGElectroencephalogramQua

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Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...
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Encephalitis is inflammation of the brain parenchyma caused by direct viral invasion or immune-mediated mechanisms triggered by infections or tumors. Both processes lead to neuronal injury, disrupted neurotransmission, and diverse neurological symptoms, often with overlapping clinical and pathological features.Autoimmune EncephalitisIn autoimmune encephalitis, antibodies target neuronal antigens on cell surfaces, synapses, or within neurons. A key example is anti-NMDAR encephalitis, which can...