Related Experiment Video

Updated: Jun 4, 2025

Investigating Target Gene Function in a CD40 Agonistic Antibody-induced Colitis Model using CRISPR/Cas9-based Technologies
09:08

Investigating Target Gene Function in a CD40 Agonistic Antibody-induced Colitis Model using CRISPR/Cas9-based Technologies

Published on: June 2, 2021

1.8K

NLRC4-associated autoinflammatory disease: Insights from mouse models and somatic variants

Mathijs Willemsen1, Willem Roosens2, Frederik Staels3

  • 1Department of Internal Medicine, Division of Rheumatology, Maastricht University Medical Center, Maastricht, The Netherlands.

The Journal of Allergy and Clinical Immunology
|December 26, 2024
PubMed
Summary

No abstract available in PubMed .

Keywords:
AutoinflammationIL-18NLRC4autoinflammatory diseasegermlineinflammasomemacrophage activation syndromesomatic

More Related Videos

The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice
12:04

The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice

Published on: November 1, 2015

17.4K
Vasodilation of Isolated Vessels and the Isolation of the Extracellular Matrix of Tight-skin Mice
08:09

Vasodilation of Isolated Vessels and the Isolation of the Extracellular Matrix of Tight-skin Mice

Published on: March 24, 2017

8.0K

Related Experiment Videos

Last Updated: Jun 4, 2025

Investigating Target Gene Function in a CD40 Agonistic Antibody-induced Colitis Model using CRISPR/Cas9-based Technologies
09:08

Investigating Target Gene Function in a CD40 Agonistic Antibody-induced Colitis Model using CRISPR/Cas9-based Technologies

Published on: June 2, 2021

1.8K
The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice
12:04

The bm12 Inducible Model of Systemic Lupus Erythematosus SLE in C57BL/6 Mice

Published on: November 1, 2015

17.4K
Vasodilation of Isolated Vessels and the Isolation of the Extracellular Matrix of Tight-skin Mice
08:09

Vasodilation of Isolated Vessels and the Isolation of the Extracellular Matrix of Tight-skin Mice

Published on: March 24, 2017

8.0K

Related Concept Videos

Autoimmune Disorders01:29

Autoimmune Disorders

385
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
385

Articles linked to this work by shared authors, journal, and citation graph.

Belgian consensus-based recommendations on the management of hospitalized patients with a penicillin allergy label.

Acta clinica Belgica·2026

Free IL-18 in NLRC4-associated autoinflammatory disease without macrophage activation syndrome.

Rheumatology (Oxford, England)·2026

The 2025 WAO Guidelines for the classification, diagnosis, and treatment of hereditary angioedema, with consideration of worldwide disparities.

The World Allergy Organization journal·2026

Hypersensitivity to Excipients in Drugs: An EAACI Position Paper.

Allergy·2026

Adult patients with autoinflammation of unknown origin partially phenocopy the immune presentation of Still's disease.

Nature communications·2026

Performance of the I3A Scoring System for Risk Stratification in a Retrospective Cohort of Children With Ibuprofen-Induced NSAID Hypersensitivity.

The journal of allergy and clinical immunology. In practice·2026

Tape-strip transcriptomics identify immune signatures in cutaneous T-cell lymphoma distinct from benign inflammatory skin diseases.

The Journal of allergy and clinical immunology·2026

Beyond Type 2 Inflammation: An Innate-Myeloid Axis is Linked to CRSwNP Recurrence.

The Journal of allergy and clinical immunology·2026

A regulatory T cell-biased IL-2 mutein inhibits the development of allergen-specific Th2 cells and allergic asthma.

The Journal of allergy and clinical immunology·2026

Congenital Ichthyosis is Associated with Increased Risk of Allergic Disorders.

The Journal of allergy and clinical immunology·2026

Construction of a chronic spontaneous urticaria-relevant IgE-mediated mouse model based on passive cutaneous anaphylaxis and its transcriptome analysis.

The Journal of allergy and clinical immunology·2026

IL-1 confers IgG-mediated protection against allergic anaphylaxis.

The Journal of allergy and clinical immunology·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us