A Case of a Large Brain Metastasis: Time for Multidisciplinary Consultation

Patients with complex diseases are mostly treated in a multidisciplinary setting. The impact of multidisciplinary care cannot be emphasized enough as it has the potential to significantly increase survival and, in some cases, help avoid a risky treatment approach. The aim of this case illustration is to emphasize the importance of multidisciplinary treatment and learn from the different approaches that can be made while treating such patients. This case describes the clinical course of a 40-year-old female patient with metastatic non-small cell lung carcinoma (NSCLC), TNM classification cT3N3M1c. Although she had clinical and radiological signs of brain herniation, a risky neurosurgical intervention was prevented due to an extensive multidisciplinary approach. Moreover, the important role of multidisciplinary consultation, imaging, and tumor markers in identifying pseudoprogression in the increasingly complex treatment of metastatic NSCLC is also demonstrated. In conclusion, a multidisciplinary approach is a crucial step in the growing complex treatment strategies for patients with brain metastases of NSCLC.