Cutaneous Metastasis of Bladder Cancer: A Systematic Review.
Nagham Bazzi1, Sadek Jaber2, Wajih A Saad3
1Department of Medicine, Baabda Governmental Hospital, Beirut, LBN.
Cureus
|December 27, 2024
Summary
Bladder cancer metastasis, though rare, carries a high mortality risk. This review of 59 cases found cutaneous lesions most commonly on the abdomen and chest, highlighting unpredictable metastasis patterns.
Area of Science:
- Uro-oncology
- Cancer Metastasis Research
- Dermatology
Background:
- Bladder cancer is a significant cause of urogenital cancer.
- Metastasis from urologic tumors, while infrequent, is linked to high mortality rates.
- The patterns and locations of bladder cancer metastasis are often unpredictable.
Purpose of the Study:
- To review and synthesize existing literature on bladder cancer metastasis.
- To identify common sites and patterns of metastasis from bladder cancer.
- To inform clinical practice by understanding metastasis characteristics.
Main Methods:
- A comprehensive literature search was conducted.
- Included 49 case reports published between 1949 and 2021.
- Analyzed data from 59 patients (50 male, 9 female).
Main Results:
- Urothelial/transitional cell carcinoma was the most common type (72.8%).
- Other reported types included adenocarcinoma, sarcoma, and renal cell carcinoma.
- Cutaneous lesions most frequently occurred on the abdomen, followed by the chest.
Conclusions:
- Bladder cancer metastasis patterns are variable and require further investigation.
- Understanding metastasis sites can aid clinicians in patient management.
- Randomized cohort studies are recommended to further elucidate metastasis patterns.
