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Related Experiment Videos

Gastrointestinal phycomycosis in 63 dogs.

R I Miller

    Journal of the American Veterinary Medical Association
    |March 1, 1985
    PubMed
    Summary

    Canine gastrointestinal phycomycosis is often pythiosis, affecting young, large male dogs with vomiting and weight loss. Diagnosis involves histological findings, and prognosis is poor, with few dogs surviving past three months.

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    Area of Science:

    • Veterinary Pathology
    • Mycology
    • Canine Infectious Diseases

    Background:

    • Gastrointestinal phycomycosis is a rare but severe condition in dogs.
    • Accurate differentiation between pythiosis and entomophthoromycosis is crucial for diagnosis and treatment.

    Purpose of the Study:

    • To analyze the clinical, histological, and etiological characteristics of canine gastrointestinal phycomycosis.
    • To differentiate between pythiosis and entomophthoromycosis in affected dogs.
    • To assess the prognosis for dogs diagnosed with these conditions.

    Main Methods:

    • Retrospective analysis of 63 canine cases with gastrointestinal phycomycosis.
    • Histopathological examination to identify causative organisms and characterize lesions.
    • Clinical data review including signalment, clinical signs, and outcomes.

    Main Results:

    • Sixty cases were diagnosed with pythiosis, and three with entomophthoromycosis.
    • Pythiosis predominantly affected young, large male dogs, presenting with vomiting and weight loss.
    • Histological findings included granulomas in the submucosa/muscularis mucosae for pythiosis and eosinophilic sleeves for entomophthoromycosis.
    • Survival rates were low, with less than 5% of dogs alive at 3 months post-diagnosis.

    Conclusions:

    • Pythiosis is the predominant form of canine gastrointestinal phycomycosis.
    • Early and accurate diagnosis based on clinical and histological features is essential.
    • The prognosis for canine gastrointestinal phycomycosis remains poor, highlighting the need for improved therapeutic strategies.

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