Transformer Dil-DenseUnet: An Advanced Architecture for Stroke Segmentation

We propose a novel architecture, Transformer Dil-DenseUNet, designed to address the challenges of accurately segmenting stroke lesions in MRI images. Precise segmentation is essential for diagnosing and treating stroke patients, as it provides critical spatial insights into the affected brain regions and the extent of damage. Traditional manual segmentation is labor-intensive and error-prone, highlighting the need for automated solutions. Our Transformer Dil-DenseUNet combines DenseNet, dilated convolutions, and Transformer blocks, each contributing unique strengths to enhance segmentation accuracy. The DenseNet component captures fine-grained details and global features by leveraging dense connections, improving both precision and feature reuse. The dilated convolutional blocks, placed before each DenseNet module, expand the receptive field, capturing broader contextual information essential for accurate segmentation. Additionally, the Transformer blocks within our architecture address CNN limitations in capturing long-range dependencies by modeling complex spatial relationships through multi-head self-attention mechanisms. We assess our model's performance on the Ischemic Stroke Lesion Segmentation Challenge 2015 (SISS 2015) and ISLES 2022 datasets. In the testing phase, the model achieves a Dice coefficient of 0.80 ± 0.30 on SISS 2015 and 0.81 ± 0.33 on ISLES 2022, surpassing the current state-of-the-art results on these datasets.