Avoidant Restrictive Food Intake Disorder in Pediatric Liver Transplant Patients

Following liver transplantation (LT), adequate nutrition is essential, as malnutrition may contribute to slower growth in pediatric patients and put patients at risk of complications following transplant. Avoidant Restrictive Food Intake Disorder (ARFID) is an eating disorder characterized by restrictive eating patterns that compromise nutrition. Patients with ARFID may have significant difficulty meeting nutritional needs due to fear of gastrointestinal distress, making it especially difficult to manage in patients following LT.

We performed a retrospective chart review of de-identified patients who received LT at our institution. Two patients with ARFID who had undergone LT were identified. Their diagnoses, clinical courses, and post LT outcomes are reported. A literature review of the presentation and diagnosis of ARFID in pediatric patients and nutritional management of pediatric LT patients was performed. No IRB review was required given the sample size of two patients, per UCSF IRB rules and regulations.

We present two unique cases of ARFID: one with onset prior to LT and one with onset following LT. Outpatient psychiatry treatment was essential for nutritional management for the patient who developed ARFID following LT. The other patient continues to see a dietitian given ongoing nausea that limits her oral intake but does not receive any psychiatric support.

ARFID and selective eating patterns are rare but notable occurrences after pediatric LT, but they may also be underreported given the novelty of ARFID and the prevalence of gastrointestinal symptoms following transplant. Our case adds to the limited literature on ARFID in children following major surgical procedures and highlights the importance of interdisciplinary care and the importance of nutritional management in pediatric patients prior to and post LT.