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Investigating changes in connected speech in nonfluent/agrammatic primary progressive aphasia following script
Stephanie M Grasso1, Karinne Berstis2, Kristin Schaffer Mendez3
1Department of Speech, Language and Hearing Sciences, University of Texas at Austin, United States.
Script training improved speech fluency and connected speech measures in individuals with nonfluent/agrammatic primary progressive aphasia (nfvPPA). This intervention demonstrated significant gains in speech production and timing post-treatment.
Area of Science:
- Speech-language pathology
- Neuroscience
- Linguistics
Background:
- Script training is a speech-language intervention that uses repeated rehearsal of functional content to improve fluent connected speech.
- It has shown benefits for individuals with aphasia and apraxia of speech, including those with primary progressive aphasia (PPA).
- Previous studies on script training in nonfluent/agrammatic PPA (nfvPPA) focused on limited outcome measures, leaving potential benefits to connected speech less understood.
Purpose of the Study:
- To evaluate the utility of a broader range of connected speech measures for assessing script training outcomes in individuals with nfvPPA.
- To characterize the effects of Video-Implemented Script Training for Aphasia (VISTA) on various speech production and timing parameters.
- To explore the application of automated and semi-automated analysis tools in quantifying treatment effects.
Main Methods:
- Twenty individuals with nfvPPA participated in the study, receiving Video-Implemented Script Training for Aphasia (VISTA).
- Trained and untrained script topics were assessed pre- and post-treatment.
- Speech samples were transcribed and analyzed using Computerized Language ANalysis (CLAN) for fluency, grammar, and informativeness, alongside acoustic measures of speech timing.
Main Results:
- Participants showed significant improvements in words per minute, reduced fluency disruptions, increased mean length of utterance, enhanced grammatical complexity, and a higher proportion of open to closed class words for trained topics.
- A reduction in mean and variability of syllable duration and mean pause duration was observed.
- The speech-to-pause ratio increased, indicating improved speech flow.
Conclusions:
- Script training effectively promotes fluency of connected speech in individuals with nfvPPA.
- The study highlights the value of comprehensive, automated, and semi-automated speech measures in evaluating the impact of speech interventions.
- These findings support script training as a beneficial therapy for improving connected speech in nfvPPA.
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