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Causes and risk factors for stillbirth in India: A systematic review protocol
N Siva1, Baby S Nayak2, Arpita Roy3
1Department of Child Health Nursing, SUM Nursing College, Siksha 'O' Anusandhan University, Bhubaneshwar, Odisha, India.
Insights
This systematic review identifies stillbirth causes and risk factors in India. Findings will inform interventions and policies to reduce stillbirth rates and improve perinatal care.
Area of Science:
- Public Health
- Perinatal Medicine
- Epidemiology
Background:
- Stillbirths represent a significant global health challenge, necessitating research into their causes and risk factors.
- Understanding these factors is crucial for developing effective interventions and improving perinatal care outcomes.
- This study focuses on the Indian context, a region with a high burden of stillbirths.
Purpose of the Study:
- To systematically identify the causes and potential risk factors associated with stillbirths in India.
- To provide evidence for targeted interventions and policy development aimed at reducing stillbirth rates.
- To enhance the quality of antenatal and perinatal care services across India.
Main Methods:
- A systematic review protocol is employed, adhering to PRISMA guidelines.
- Inclusion of all observational study designs (cross-sectional, descriptive, cohort, case-control) from India.
- Comprehensive literature search across global and Indian databases, supplemented by hand searching and reference list scrutiny. Independent screening, data extraction, and quality appraisal by two reviewers using the Joanna Briggs Institute Critical Appraisal Checklist.
Main Results:
- The systematic review will identify and highlight key causes and potential risk factors for stillbirths in India.
- Results will guide healthcare teams in developing standardized protocols and policies for antenatal care and early interventions.
- The findings aim to improve access to quality healthcare, particularly in rural and underserved areas.
Conclusions:
- The identified causes and risk factors for stillbirth in India address a critical knowledge gap.
- This research will form the basis for targeted interventions and evidence-based policy recommendations.
- The study contributes to improving the healthcare system's trajectory in reducing stillbirth rates.
Objectives:
Stillbirths, the tragic loss of a baby before or during delivery, presents a profound global health concern. Investigating the diverse causes and risk factors is essential to develop targeted interventions, enhance perinatal care, and reduce the incidence of this devastating outcome. The aim of this study was to identify the causes and possible risk factors of stillbirths in India.
Study Design:
The study design is a protocol for systematic review.
Methods:
This systematic review will include all types of observational studies, such a cross-sectional surveys, descriptive studies, cohort studies and case-control studies from India. Studies will be retrieved from global databases like CINAHL, Medline through PubMed, EMBASE, SCOPUS, Web of Science, ProQuest Medical Library, Microsoft Academia, DOAJ, and Indian databases like Indian Citation Index, J-Gate, and Neonatal Database using database-specific keywords. Additionally, online hand searching will be done on the websites of the relevant Indian institutions. Primary studies' reference lists will be scrutinized for additional references if required. Two review authors (SN & AR) will independently screen, extract data, and critically appraise included studies. The Joanna Briggs Institute Critical Appraisal Checklist will be used to identify the quality and risk of bias of included studies. Any disagreements will be resolved in consultation with a third reviewer (BSN).
Results:
Results will be reported as per the PRISMA guidelines. This systematic review will. identify and highlight the causes and potential risk factors of stillbirths in India, which will guide the healthcare team in planning and developing a standard protocol and policies to promote successful antenatal care, implement effective early interventions, and improve access to quality healthcare to reduce stillbirth rates in institutional, rural, and underserved areas as per the Indian healthcare system.
Conclusion:
These findings on causes and risk factors for stillbirth in India address a crucial gap in th literature and allow us to prepare a foundation for targeted interventions and policy recommendations in the healthcare system trajectory.
Protocol Registration:
The Protocol is registered in the International Prospective Register of Systematic reviews PROSPERO (CRD - 42024506186).
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