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N6-methyladenosine (m6A) modification: Emerging regulators in plant-virus interactions
Yanjun Li1, Jianping Chen1, Zongtao Sun1
1State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Key Laboratory of Biotechnology in Plant Protection of MARA, Key Laboratory of Green Plant Protection of Zhejiang Province, Institute of Plant Virology, Ningbo University, Ningbo, 315211, China.
Virology
|December 27, 2024
Summary
N6-methyladenosine (m6A) regulates plant-virus interactions. This review summarizes m6A
Area of Science:
- Epigenetics
- Plant Virology
- Molecular Biology
Background:
- N6-methyladenosine (m6A) is a prevalent, reversible RNA modification influencing RNA fate and function.
- m6A involves methyltransferases (writers), demethylases (erasers), and m6A-binding proteins (readers).
- m6A's role in animal virus-host interactions is established, but its role in plant viruses is emerging.
Purpose of the Study:
- To review current knowledge on the functions and molecular mechanisms of m6A in plant-virus interactions.
- To highlight the early stage of research in this field.
Main Methods:
- Review of existing literature on m6A modifications in plant-virology.
- Summary of findings from recent sequencing technologies enabling genome-wide m6A mapping.
Main Results:
- m6A modification plays a significant role in regulating plant-virus interactions.
- Understanding these interactions is crucial for deciphering viral infection mechanisms in plants.
Conclusions:
- Further research into m6A in plant-virus interactions is needed.
- Insights gained may lead to novel antiviral strategies for controlling plant viral diseases.
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