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Updated: May 8, 2025

RNA Next-Generation Sequencing and a Bioinformatics Pipeline to Identify Expressed LINE-1s at the Locus-Specific Level
Published on: May 19, 2019
LCRAnnotationsDB: a database of low complexity regions functional and structural annotations
Joanna Ziemska-Legiecka1, Patryk Jarnot2, Sylwia Szymańska2
1Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, 02-106, Poland. joannazl@ibb.waw.pl.
Abstract:
Low Complexity Regions (LCRs) are segments of proteins with a low diversity of amino acid composition. These regions play important roles in proteins. However, annotations describing these functions are dispersed across databases and scientific literature. LCRAnnotationsDB aims to consolidate knowledge about LCRs and store relevant annotations in a single place. To unify redundant annotations, we assigned them categories based on similarity in function, protein structure, and biological process. Categories are organized hierarchically by linking them to Gene Ontology terms. The LCRAnnotationsDB database can be accessed at https://lcrannotdb.lcr-lab.org/ .
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