[Neurological complications resulting of nitrous oxide intoxication]

Nitrous oxide (NO) intoxication is a common consequence of its inhalation with recreational purpose, which is prevalent among young people. The most severe result of such an entertainment is development of myelopolyneuropathy with polyneuropathy as the most common presentation, which may start acutely or subacutely. The underlying cause of neurological complications of NO intoxication is deficit of B₁₂ vitamin, however its laboratory confirmation may be challenging. The key aspect of treatment of neurological symptoms in such patients is prescription of adequate dosage of B₁₂ for a long period of time. In this paper we present the clinical case, which demonstrates challenges of vitamin B₁₂ deficiency verification and advantages of oral cyanocobalamin prescription.