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Diagnostic value of hemoglobin concentration in identifying Meckel's diverticulum in pediatric lower gastrointestinal

Miguel Couselo1, Vicente Ibáñez2, Beatriz Pemartín3

  • 1Pediatric Surgery Department, Hospital Universitari i Politècnic La Fe, Av/Fernando Abril Martorell 106, 46026, Valencia, Spain. miguelcjerez@hotmail.com.

Pediatric Surgery International
|December 28, 2024
PubMed

Insights

Low hemoglobin levels in children with lower gastrointestinal bleeding (LGIB) can help diagnose Meckel's diverticulum (MD). This finding aids surgical decisions for pediatric LGIB cases.

Area of Science:

  • Pediatric Gastroenterology
  • Surgical Diagnostics
  • Hematology

Background:

  • Lower gastrointestinal bleeding (LGIB) in children presents diagnostic challenges.
  • Meckel's diverticulum (MD) is a common cause of LGIB requiring accurate diagnosis.
  • Differentiating MD from other causes of LGIB is crucial for appropriate management.

Purpose of the Study:

  • To evaluate the diagnostic accuracy of hemoglobin concentration for identifying Meckel's diverticulum (MD) in pediatric patients.
  • To determine if hemoglobin levels can assist in surgical decision-making for children experiencing LGIB.

Main Methods:

  • Retrospective cohort study of pediatric LGIB cases (2011-2021).
  • Comparison of hemoglobin levels and clinical variables between patients with confirmed MD (MeckD) and those without (non-MeckD).
  • Receiver operating characteristic (ROC) curve analysis to assess diagnostic performance of hemoglobin for MD.

Main Results:

  • Hemoglobin levels were significantly lower in the Meckel's diverticulum group (8.7 g/dL) compared to the non-Meckel's diverticulum group (12.6 g/dL).
  • Hemoglobin concentration ≤ 8.3 g/dL demonstrated high specificity (≥99.01%) and a positive likelihood ratio (≥35.8) for diagnosing MD.
  • The area under the ROC curve was 0.91, indicating strong diagnostic performance.

Conclusions:

  • Hemoglobin concentration exhibits significant diagnostic value for Meckel's diverticulum in children.
  • Low hemoglobin levels can serve as a valuable indicator to guide surgical interventions in pediatric LGIB management.
Abstract

Keywords:
ChildDiagnosisGastrointestinal hemorrhageHemoglobinMeckel diverticulum

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