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[Long-COVID, severe course, with congenital bronchiectasis, Williams-Campbell syndrome. Case report]

S A Pribylov1,2, T A Maslova2, V S Pribylov1

  • 1Kursk State Medical University.

Terapevticheskii Arkhiv
|December 28, 2024
PubMed

Insights

This case study details an 18-year-old female with congenital bronchiectasis, cystic lung disease, and severe long-COVID, highlighting complex respiratory conditions. The report covers her treatment journey and preparation for lung transplantation.

Area of Science:

  • Pulmonology
  • Infectious Diseases
  • Genetics

Background:

  • Congenital bronchiectasis and cystic lung disease are rare conditions.
  • Williams-Campbell syndrome is a rare genetic disorder affecting lung development.
  • Long-COVID can lead to severe respiratory complications, particularly in individuals with pre-existing lung conditions.

Observation:

  • An 18-year-old female presented with a severe case of congenital bronchiectasis and bilateral upper lobe cystic lung degeneration.
  • The patient was diagnosed with Williams-Campbell syndrome and experienced a severe course of long-COVID.
  • She required multiple treatments in infectious disease and pulmonology departments, ultimately being evaluated for lung transplantation.

Findings:

  • The case highlights the complex interplay between congenital lung abnormalities and severe COVID-19.
  • Successful management required multidisciplinary care, including infectious disease and pulmonology specialists.
  • Lung transplantation was considered a necessary intervention due to the severity of her respiratory failure.

Implications:

  • This case underscores the importance of early diagnosis and comprehensive management for patients with rare congenital lung diseases.
  • It emphasizes the potential for severe respiratory outcomes in individuals with underlying lung conditions who contract COVID-19.
  • The case provides insights into the indications and logistics of lung transplantation for complex respiratory failure in young patients.

Keywords:
Williams–Campbell syndromecongenital bronchiectasiscystic lung degenerationlong-COVIDpulmonary heartpulmonary hypertension

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