Related Experiment Video
Updated: Jun 4, 2025

3D Ultrasound Imaging: Fast and Cost-effective Morphometry of Musculoskeletal Tissue
Published on: November 27, 2017
Acute muscle loss in elderly hospitalized patients: Risk factors and adverse clinical outcomes
Objective:
To assess muscle loss via ultrasound in the elderly and its link to clinical outcomes and risk factors.
Methods:
This retrospective cohort study assessed muscle loss in hospitalized elderly via ultrasound, comparing bilateral anterior thigh thickness (BATT) at admission and after seven days, exploring its relation to hospital-acquired complications (HACs).
Results:
In 86 patients (mean age 83.6), a 4.2% BATT decline over a week was seen, with 39.5% losing more than 10%. BATT changes correlated with HACs, with a -10% change as a predictive threshold. Risk factors for severe muscle loss in elderly hospitalized patients include female gender, higher baseline nutrition risk screening 2002 (NRS2002) scores and higher level of coefficient of variation of red blood cell distribution width (RDW-CV).
Conclusions:
Elderly hospitalized patients were at risk of acute muscle loss during their hospital stay. Severe BATT decline during hospitalization in elderly patients was independently associated with HACs.
More Related Videos
Related Concept Videos
Skeletal Muscle Relaxants: Adverse Effects
Unlike...
Disorders of the Skeletal Muscle
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
Cross-bridge Cycle
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Myasthenia Gravis: Overview and Treatment
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
Myasthenia Gravis: Diagnostic Tests
The edrophonium test is a diagnostic tool for myasthenia gravis. It involves...

