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Updated: May 8, 2025

Author Spotlight: Quantifying Pain Experience – An Illustrative Approach Using the Pain Body Diagram
Published on: July 7, 2023
["Mixed pain": Current conceptualization and approach for Primary Care]
1Centro de Salud Trujillo, Consultorios de Herguijuela/Conquista de la Sierra, Cáceres, España; Miembro del Grupo de Trabajo de Dolor y Cuidados Paliativos de SEMERGEN.
Abstract:
Despite being referenced in the literature for over a decade, the term "mixed pain" has hardly been formally defined. The strict binary classification of pain as purely neuropathic or nociceptive left a good proportion of patients unclassified; even the introduction of the term "nociplastic pain" in the International Association for the Study of Pain terminology leaves out patients who clinically present with a substantial overlap of nociceptive, neuropathic, and nociplastic symptoms. For these patients the term "mixed pain" is becoming increasingly recognized and accepted by the scientific community. This narrative review summarizes the highlights of mixed pain and emphasizes the importance of recognizing this type of pain in clinical practice.
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