The Integrated Multidisciplinary Pathway for Large-Scale Management of Dyslipidemia in High-Risk Patients (ENNA)...

Area of Science:

• Cardiology
• Public Health
• Pharmacology

Background:

• Atherosclerotic cardiovascular disease (ASCVD) is a major global health burden.
• Hypercholesterolemia is a key modifiable risk factor for ASCVD.
• Suboptimal management of low-density lipoprotein cholesterol (LDL-C) contributes to high cardiovascular event rates despite available therapies.

Purpose of the Study:

• To address suboptimal lipid management in high-risk patients in Enna, Sicily.
• To optimize LDL-C control through an integrated, multidisciplinary care model.
• To increase the achievement of LDL-C target levels in high-risk populations.

Main Methods:

• The intEgrated multidiscipliNary pathway for large-scale maNagement of dyslipidemiA in high-risk patients (ENNA) Project utilized data-driven patient identification (prescription claims, lab results, discharge data).
• Collaboration between pharmacists, general practitioners (GPs), and cardiologists was central to the care model.
• GPs initiated/optimized lipid-lowering therapy, while cardiologists managed complex cases.

Main Results:

• The ENNA Project aimed to improve LDL-C control and therapeutic adherence in high-risk patients.
• The integrated care model facilitated a patient-centered approach to dyslipidemia management.
• Data-driven identification enabled targeted interventions for patients needing optimized lipid management.

Conclusions:

• Integrated, multidisciplinary care models can effectively improve LDL-C management in high-risk populations.
• Enhanced collaboration among healthcare providers optimizes patient outcomes for atherosclerotic cardiovascular disease.
• The ENNA Project demonstrates a scalable pathway for improving lipid management and reducing cardiovascular risk.