TD-STrans: Tri-domain sparse-view CT reconstruction based on sparse transformer

Sparse-view computed tomography (CT) speeds up scanning and reduces radiation exposure in medical diagnosis. However, when the projection views are severely under-sampled, deep learning-based reconstruction methods often suffer from over-smoothing of the reconstructed images due to the lack of high-frequency information. To address this issue, we introduce frequency domain information into the popular projection-image domain reconstruction, proposing a Tri-Domain sparse-view CT reconstruction model based on Sparse Transformer (TD-STrans).

TD-STrans integrates three essential modules: the projection recovery module completes the sparse-view projection, the Fourier domain filling module mitigates artifacts and over-smoothing by filling in missing high-frequency details; the image refinement module further enhances and preserves image details. Additionally, a multi-domain joint loss function is designed to simultaneously enhance the reconstruction quality in the projection domain, image domain, and frequency domain, thereby further improving the preservation of image details.

The results of simulation experiments on the lymph node dataset and real experiments on the walnut dataset consistently demonstrate the effectiveness of TD-STrans in artifact removal, suppression of over-smoothing, and preservation of structural fidelity.

The reconstruction results of TD-STrans indicate that sparse transformer across multiple domains can alleviate over-smoothing and detail loss caused by reduced views, offering a novel solution for ultra-sparse-view CT imaging.