Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Anatomical Positions01:11

Anatomical Positions

9.7K
In anatomy, several standard anatomical positions are used as references for describing the position and orientation of different body parts. These positions help provide a common frame of reference when discussing anatomical structures. The anatomical position is the standard reference point for describing the body's position and orientation. In this position:
The body is upright, facing forward, and standing erect.
The feet are parallel and flat on the floor.
The arms are hanging by the...
9.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Robustness of Tumor Control Against Intrafraction Patient Motion in Lung Stereotactic Body Radiation Therapy.

Advances in radiation oncology·2026
Same author

A 10-Year Patterns of Use Analysis for the World's First Commercial Compact Pencil Beam Scanning Proton Therapy System.

International journal of radiation oncology, biology, physics·2026
Same author

Multiinstitutional survey of source modeling parameters for proton pencil beam scanning treatment planning system commissioning.

Medical physics·2025
Same author

Workflow Efficiency in Vaginal Cuff High Dose Rate Brachytherapy Using Artificial Intelligence-Based Organ Segmentation and Multi-Channel Cylinder Modeling.

Cancers·2025
Same author

AAPM Task Group No. 249.B-Essentials and guidelines for clinical medical physics residency training programs.

Journal of applied clinical medical physics·2025
Same author

Commissioning of a reference beam model-based Monte Carlo dose calculation algorithm for cranial stereotactic radiosurgery.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)·2025

Related Experiment Video

Updated: Jun 4, 2025

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
08:17

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Published on: June 7, 2015

15.7K

Patient Positional Uncertainty and Margin Reduction in Lung Stereotactic Ablative Radiation Therapy Using Pneumatic

Yohan A Walter1, Chiachien J Wang2, Daniel B Speir2

  • 1Department of Clinical Research, University of Jamestown, Fargo, North Dakota; Department of Radiation Oncology, Willis Knighton Cancer Center, Shreveport, Louisiana.

Practical Radiation Oncology
|December 29, 2024
PubMed
Summary

Modern lung stereotactic ablative radiation therapy (SABR) techniques allow for reduced planning target volume (PTV) margins. Intrafraction repositioning significantly decreases margin requirements, minimizing healthy tissue exposure.

More Related Videos

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy
08:54

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy

Published on: May 8, 2018

14.2K
Stereotactic Radiosurgery for Gynecologic Cancer
10:35

Stereotactic Radiosurgery for Gynecologic Cancer

Published on: April 17, 2012

18.1K

Related Experiment Videos

Last Updated: Jun 4, 2025

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
08:17

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Published on: June 7, 2015

15.7K
Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy
08:54

Treatment of Liver Metastases Using an Internal Target Volume Method for Stereotactic Body Radiotherapy

Published on: May 8, 2018

14.2K
Stereotactic Radiosurgery for Gynecologic Cancer
10:35

Stereotactic Radiosurgery for Gynecologic Cancer

Published on: April 17, 2012

18.1K

Area of Science:

  • Radiation Oncology
  • Medical Physics

Background:

  • Motion management is crucial in thoracic stereotactic ablative radiation therapy (SABR).
  • Current standard planning target volume (PTV) margins of 5.0 mm may be excessive with advanced techniques.
  • Reassessing PTV margins is warranted due to advancements in tumor localization and motion management.

Purpose of the Study:

  • To analyze intrafraction repositioning data for lung SABR under forced shallow breathing.
  • To determine appropriate planning target volume (PTV) margin requirements for modern lung SABR delivery techniques.

Main Methods:

  • Retrospective analysis of 607 lung SABR fractions from 124 patients treated with pneumatic abdominal compression and 4-dimensional (4D) cone beam computed tomography (4D CBCT)-guided intrafraction repositioning.
  • Calculation of margin requirements using the 2-standard deviation (SD) method and an analytical model accounting for systematic and random errors.

Main Results:

  • 85.7% of fractions had 3D repositioning shifts under 5.0 mm.
  • Margins calculated by the 2-SD method were 3.62 mm (right-left), 4.34 mm (inferior-superior), and 3.50 mm (posterior-anterior).
  • Analytical modeling suggested margins of 4.01 mm, 4.37 mm, and 3.95 mm; intrafraction repositioning reduced margin needs by 0.73 mm.

Conclusions:

  • The standard 5.0-mm PTV margin is likely conservative for workflows utilizing advanced techniques like 4D CT and 4D CBCT-guided intrafraction repositioning.
  • These modern techniques can significantly reduce required margins, thereby decreasing radiation dose to healthy tissues.
  • Caution is advised when reducing margins; a formal risk assessment is recommended before adopting new PTV margin standards.