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Updated: May 7, 2025

In Situ Immunofluorescent Staining of Autophagy in Muscle Stem Cells
Published on: June 12, 2017
Application of autophagy in mesenchymal stem cells
Min Chai1, Chun-Yan Zhang2, Shuai Chen3
1Department of Emergency Medicine, The First Hospital of Jilin University, Changchun 130000, Jilin Province, China.
Abstract:
In this editorial, we have taken an in-depth look at the article published by Wan et al. The study showed that preconditioning mesenchymal stem cells (MSCs) protected them against programmed cell death, and increased their survival rate and therapeutic potential. Autophagy, a type of programmed cell death, is a major intracellular degradation and recycling pathway that is crucial for maintaining cellular homeostasis, self-renewal, and pluripotency. We have explored the relationship between autophagy and MSCs to determine the role of autophagy in the therapeutic applications of MSCs.
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