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Ultrasonography

Ultrasonography

Ultrasonography is an imaging technique that uses high-frequency sound waves to visualize the body's internal structures. It is a non-invasive and safe procedure that does not involve the use of ionizing radiation, making it widely used in various medical fields. Ultrasonography is used to study heart function, blood flow in the neck or extremities, certain conditions such as gallbladder disease, and fetal growth and development.
During an ultrasonography procedure, a handheld device called a...

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Updated: Jun 23, 2026

High-resolution Fiber-optic Microendoscopy for in situ Cellular Imaging

High-resolution Fiber-optic Microendoscopy for in situ Cellular Imaging

Published on: January 11, 2011

Robust High-Resolution Fine OCT Needle for Side-Viewing Interstitial Tissue Imaging.

Yicong Wu¹, Jiefeng Xi¹, Li Huo¹

¹Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21205 USA.

IEEE Journal of Selected Topics in Quantum Electronics : a Publication of the IEEE Lasers and Electro-Optics Society

|December 30, 2024

Summary

This summary is machine-generated.

New optical coherence tomography (OCT) imaging needles improve biopsy procedures. These fine OCT needles offer enhanced optical and mechanical performance for minimally invasive interstitial imaging and image-guided biopsy.

Keywords:

Astigmatism OCT needle biopsy needle interstitial imaging optical coherence tomography (OCT)

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Last Updated: Jun 23, 2026

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3D Imaging of Soft-Tissue Samples using an X-ray Specific Staining Method and Nanoscopic Computed Tomography

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Published on: October 24, 2019

Area of Science:

Biomedical Engineering
Medical Imaging
Optical Engineering

Background:

Standard biopsy needles lack real-time imaging capabilities.
Integrating imaging into biopsy tools is crucial for minimally invasive procedures.
Previous OCT needle designs faced challenges with optical quality and robustness.

Purpose of the Study:

To develop fine optical coherence tomography (OCT) imaging needles integrated with standard biopsy needles.
To enhance optical quality and mechanical robustness of OCT imaging needles.
To enable real-time, cross-sectional imaging for image-guided biopsy.

Main Methods:

Developed a novel optics design encasing a fiber-optic lens and microreflector within a microglass tube.
Minimized cylindrical lens effects from the glass tube.
Integrated the miniature imaging needle with a 1300-nm swept-source OCT system for ex vivo tissue imaging.

Main Results:

Achieved improved mechanical and optical performance of the OCT imaging needle.
Demonstrated successful real-time cross-sectional OCT imaging of various ex vivo tissue samples.
The new design simplifies the needle assembly process.

Conclusions:

The developed fine OCT imaging needle shows significant potential for minimally invasive interstitial imaging.
This technology can enhance image-guided biopsy procedures.
Further development could lead to improved diagnostic accuracy and patient outcomes.