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Extramedullary Intradural Primary Spinal Angiosarcoma: A Case Study
Miguel Catalo1, Mariana Afonso2, António Verdelho3
1Radiation Oncology, Instituto Português de Oncologia do Porto Francisco Gentil, Porto, PRT.
Cureus
|December 30, 2024
Summary
This study reports an extremely rare intradural extramedullary spinal angiosarcoma in a woman. Multidisciplinary treatment, including surgery and radiation therapy, achieved disease control.
Area of Science:
- Oncology
- Neurology
- Pathology
Background:
- Angiosarcoma is a rare soft tissue sarcoma.
- Primary intradural extramedullary spinal angiosarcomas are exceptionally rare, with few documented cases.
- This study focuses on a unique case of non-vertebral origin.
Observation:
- A 51-year-old woman presented with paraparesis and constipation.
- Magnetic resonance imaging (MRI) revealed a well-demarcated, enhancing intradural extramedullary spinal lesion.
- Histological, immunohistochemical, and genetic analyses confirmed angiosarcoma.
Findings:
- The patient underwent surgery and adjuvant radiation therapy (RT).
- The patient remains stable with no signs of recurrence after three years of follow-up.
- Diagnosis presented challenges due to the rarity of the condition.
Implications:
- A multidisciplinary approach involving surgery and adjuvant RT can effectively manage spinal angiosarcoma.
- Despite a generally poor prognosis, successful disease control is achievable.
- This case highlights the importance of considering rare diagnoses in spinal oncology.
