Contrasting topologies of synchronous and asynchronous functional brain networks
Contact us if these videos are not relevant.
Contact us if these videos are not relevant.
View abstract on PubMed
Summary
This summary is machine-generated.This study introduces asynchronous functional networks (aFNs) and compares them to synchronous functional networks (sFNs) using fMRI data. aFNs reveal unique brain connectivity patterns, offering complementary insights to traditional sFN analysis.
Area Of Science
- Neuroscience
- Network Neuroscience
- Computational Neuroscience
Background
- Synchronous functional networks (sFNs) are commonly used in network neuroscience.
- Novel methods are needed to explore alternative functional brain connectivity measures.
Purpose Of The Study
- To introduce and characterize asynchronous functional networks (aFNs) generated using optimal causation entropy.
- To compare the topological properties of aFNs with traditional sFNs.
- To investigate the influence of age on network efficiency and connection probabilities in both aFNs and sFNs.
Main Methods
- Functional magnetic resonance imaging (fMRI) data from 212 participants were analyzed.
- Asynchronous functional networks (aFNs) were generated using optimal causation entropy.
- Synchronous functional networks (sFNs) were generated using correlation-based methods.
- Multivariate mixed effects models were employed to assess age-related interactions with network properties.
Main Results
- After controlling for network density, aFNs exhibited higher global efficiency but lower local efficiency compared to sFNs.
- Key nodes for outgoing global efficiency in aFNs were identified in the brainstem and orbitofrontal cortex.
- Nodes with high incoming global efficiency in aFNs were associated with the default mode network in sFNs.
- Age interacted with global efficiency in aFNs and local efficiency in sFNs to affect connection probability.
Conclusions
- Both aFNs and sFNs provide distinct and complementary information about functional brain connectivity.
- aFNs offer a novel perspective on brain network dynamics beyond synchronous correlations.
- The findings highlight the importance of considering different network metrics for a comprehensive understanding of brain function.
Contact us if these videos are not relevant.
Contact us if these videos are not relevant.
Related Concept Videos
The reticular formation is a complex network of gray and white matter located within the brainstem extending from the medulla to the midbrain.
Within the reticular formation, there are several distinct nuclei that can be classified into three broad categories. The Raphe nuclei are located along the midline of the brainstem. They are primarily known for their role in synthesizing and releasing serotonin, a neurotransmitter involved in regulating mood, appetite, sleep, and circadian rhythms. The...
The limbic system, often called the "emotional brain," is a complex set of structures located deep within the brain. The intricate network of the limbic system supports a wide range of psychological functions, from emotional regulation to memory formation and sensory processing. This functional brain region encompasses specific parts of the diencephalon and the cerebrum, integrating the higher mental functions of the cerebral cortex with the primitive emotional responses of the deep...
The brain is an integral component of the nervous system and serves as the center for processing sensory inputs, making decisions, and directing bodily actions. This complex organ is organized into three primary sections: the hindbrain, midbrain, and forebrain, each responsible for a range of vital functions.
Hindbrain
The hindbrain, located at the base of the brain, plays a vital role in regulating automatic processes that sustain life. It includes the medulla oblongata, which is essential for...
The nervous system, responsible for sensing, integrating, and responding to various stimuli, is divided into the central nervous system (CNS) and the peripheral nervous system (PNS). The PNS has two functional divisions: the sensory or afferent division and the motor or efferent division.
The sensory division transmits information from sensory receptors in the body to the CNS. It provides the CNS with knowledge about somatic senses (such as tactile, thermal, pain, and proprioceptive sensations)...
The brain is the most complex organ in the human body. It consists of four main parts: the cerebrum, diencephalon, cerebellum, and brainstem.
The cerebrum is the largest section of the brain and divides into left and right hemispheres, separated by a deep fissure. The cerebral outer layer of grey matter — the cerebral cortex — comprises elevations called gyri and shallow groves called sulci. The inner portion of white matter includes long nerve fibers known as axons, which connect...