Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Muscle function studies in amputated lathyritic rats.

V L Yeager

    The Journal of Experimental Zoology
    |February 1, 1985
    PubMed
    Summary

    Evaluating muscle function changes after leg amputation in rats using muscle weight and exostosis size revealed differing results. Both methods reflect functional changes, but their distinct mechanisms mean outcomes may not always align.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The performance of students selected through a special program at St. Louis University School of Medicine.

    Academic medicine : journal of the Association of American Medical Colleges·1997
    Same author

    Learning gross anatomy: dissection and prosection.

    Clinical anatomy (New York, N.Y.)·1996
    Same author

    Anatomy of the lumbar vertebral column.

    Seminars in neurology·1986
    Same author

    The degree to which accuracy of preoperative staging of laryngeal carcinoma has been enhanced by computed tomography.

    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery·1986
    Same author

    Smooth muscle in the hepatic artery, portal vein and hepatic vein within the liver of the raccoon and guinea pig.

    Experientia·1985
    Same author

    Lathyrism: mini-review and a comment on the lack of effect of protease inhibitors on osteolathyrism.

    Journal of experimental pathology·1985

    Area of Science:

    • Biomedical Engineering
    • Muscle Physiology
    • Surgical Research

    Background:

    • Muscle function evaluation is crucial after amputation.
    • Lathyrus odoratus diet induces exostoses at muscle attachment sites in rats.
    • Understanding compensatory muscle changes is vital for rehabilitation.

    Purpose of the Study:

    • To compare muscle weight changes and exostosis size as indicators of muscle function post-amputation.
    • To investigate the correlation between muscle atrophy/hypertrophy and exostosis development.
    • To determine the reliability of these two methods in reflecting functional alterations.

    Main Methods:

    • Rats underwent left hind limb amputation below the knee.
    • A 50% Lathyrus odoratus diet was administered to induce exostoses.
    • Muscle weights (atrophy/hypertrophy) and exostosis sizes were assessed at 3, 6, and 9 weeks.

    Main Results:

    • Left adductor longus and quadratus femoris showed atrophy with smaller exostoses.
    • Left iliopsoas exhibited hypertrophy with larger exostoses.
    • Left pectineus showed hypertrophy but smaller exostoses, indicating a discrepancy.

    Conclusions:

    • Both muscle weight changes and exostosis size changes reflect muscle function alterations post-amputation.
    • Discrepancies arise because muscle weight and exostosis size respond via different physiological mechanisms.
    • These methods provide complementary, but not always concordant, data on muscle function changes.

    Related Experiment Videos