Related Experiment Video
Updated: May 7, 2025

Use of Hematopoietic Stem Cell Transplantation to Assess the Origin of Myelodysplastic Syndrome
Published on: October 3, 2018
Huge extramedullary hematopoiesis mass in the posterior mediastinum: a case report
Zhao Junjun1, Dong Lingjun1, Ma Zhifeng1
1Department of Thoracic Surgery, Shaoxing People's Hospital, Shaoxing, Zhejiang, China.
Background:
Extramedullary hemopoiesis (EMH) is a rare condition characterized by abnormal blood cell production outside the bone marrow, commonly occurring in the liver, spleen, lymph nodes, and less frequently in the mediastinum.
Case Presentation:
This case involves a 68-year-old male patient who was found to have a posterior mediastinal mass upon examination. A surgical biopsy was performed, and pathological examination confirmed it to be extramedullary hemopoiesis (EMH). Further investigation revealed that the patient also suffered from hemolytic anemia.
Conclusions:
The report presents a case of a large posterior mediastinal mass, which was confirmed to be extramedullary hemopoiesis (EMH) upon surgical pathology. It is challenging to differentiate posterior mediastinal tumors from EMH, and the possibility of EMH should be considered in patients with posterior mediastinal masses that have similar CT findings and laboratory test results.
Related Concept Videos
Hematopoiesis
Overview of Hematopoiesis
Developmental Phases of Hematopoiesis
Initially, HSCs are formed in the embryonic yolk sac, a critical site for early blood cell production. These stem cells subsequently migrate to other...

