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Hypertension Management in Women With a Multidisciplinary Approach
Niloofar Nobakht1, Yalda Afshar2, Marmar Vaseghi3
1Division of Nephrology, Department of Medicine, at the David Geffen School of Medicine at University of California, Los Angeles, CA, USA.
Insights
Hypertension management in women requires tailored approaches due to unique biological and social factors. This review highlights sex-specific considerations for effective hypertension control throughout women's lives.
Area of Science:
- Cardiovascular Medicine
- Women's Health
- Hypertension Research
Background:
- Current hypertension guidelines often overlook sex-specific differences in disease mechanisms.
- Limited contemporary reviews comprehensively address hypertension in women across their lifespan.
Purpose of the Study:
- To review unique characteristics of hypertension in women.
- To identify challenges and multidisciplinary strategies for hypertension control in women.
- To highlight sex-specific treatment approaches and knowledge gaps.
Main Methods:
- Comprehensive literature search of PubMed, OVID, EMBASE, and Cochrane databases (1995-2023).
- Focused on clinical studies, management challenges, and multidisciplinary approaches for women's hypertension.
- Included unique issues for racial and ethnic minority groups.
Main Results:
- Numerous challenges persist despite understanding hypertension mechanisms in women.
- Differences exist in lifestyle modification and drug therapy efficacy between sexes.
- Sleep, socioeconomic disparities, and access to care significantly impact hypertension in women.
Conclusions:
- Optimal hypertension control in women necessitates a multidisciplinary, sex-specific approach.
- Future research should address knowledge gaps, particularly regarding life stages and socioeconomic factors.
- Tailored strategies are crucial for managing hypertension from premenopause through menopause.
Abstract:
Current clinical practice guidelines were established by several organizations to guide the diagnosis and treatment of hypertension in men and women in a similar manner despite data demonstrating differences in underlying mechanisms. Few publications have provided a contemporary and comprehensive review focused on characteristics of hypertension that are unique to women across their life spectrum. We performed a computerized search using PubMed, OVID, EMBASE, and Cochrane library databases between 1995 and 2023 that highlighted relevant clinical studies, challenges to the management of hypertension in women, and multidisciplinary approaches to hypertension control in women, including issues unique to racial and ethnic minority groups. Despite our current understanding of underlying mechanisms and strategies to manage hypertension in women, numerous challenges remain. Here, we discuss potential factors contributing to hypertension in women, differences related to effects of lifestyle modifications and drug therapy between men and women, the impact of sleep, and the importance of recognizing disparities in socioeconomic conditions and access to care. This review outlines several opportunities for future studies to fill gaps in knowledge to achieve optimal control of hypertension in women using a multidisciplinary approach, particularly related to sex-specific treatment approaches while considering socioeconomic conditions and life stages from premenopause through the transition to menopause.
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