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Related Experiment Video

Updated: Jul 8, 2026

Image Acquisition Method for the Sonographic Assessment of the Inferior Vena Cava
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Two-Year Outcomes from the Cook Inferior Vena Cava Filter (CIVC) Study.

Richard J Van Allan1, H Bob Smouse2, Richard G McWilliams3

  • 1Section of Interventional Radiology, Department of Imaging, Cedars-Sinai Medical Center, Los Angeles, California.

Journal of Vascular and Interventional Radiology : JVIR
|December 30, 2024
PubMed
Summary

The Celect and Günther Tulip Vena Cava Filters demonstrated safety and effectiveness in preventing pulmonary embolism (PE) over 2 years. This study supports their use in patients requiring inferior vena cava (IVC) filter placement.

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Area of Science:

  • Vascular Surgery
  • Interventional Radiology
  • Cardiology

Background:

  • Pulmonary embolism (PE) remains a significant cause of morbidity and mortality.
  • Inferior vena cava (IVC) filters are used to prevent PE in high-risk patients.
  • Continued evaluation of IVC filter safety and effectiveness is crucial.

Purpose of the Study:

  • To report 2-year outcomes of the Celect and Günther Tulip IVC filters.
  • To assess the safety and effectiveness of these filters in a prospective, multicenter study.
  • To evaluate filter placement success, PE prevention, and adverse events.

Main Methods:

  • A prospective, multicenter, single-arm study (CIVC) enrolled 473 patients.
  • Patients received either Celect or Günther Tulip IVC filters for PE prevention.
  • Follow-up extended to 2 years, assessing technical success, symptomatic PE, and major adverse events.

Main Results:

  • Technical placement success rate was 97.8%.
  • The primary safety rate was 86.7% in post hoc analysis (P = .001).
  • Successful filter retrieval occurred in 94.9% of cases, with minimal device-related complications.

Conclusions:

  • The Celect and Günther Tulip IVC filters are safe and effective for PE prevention.
  • The study supports the long-term use of these devices in appropriate patient populations.
  • Further research may focus on optimizing patient selection and long-term outcomes.