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Bullous Pyoderma Gangrenosum Associated with Antiphospholipid Syndrome: A Case Report and Literature Review
Mayar Al-Bahrani1, Yousuf Alwashahi2, Ahmed Almoqbali3
1Family Medicine General Foundation Program, Oman Medical Specialty Board, Muscat, Oman.
Oman Medical Journal
|December 31, 2024
Abstract:
We report a rare case of a middle-aged Omani woman who was known to have primary antiphospholipid syndrome, glucose-6-phosphate dehydrogenase deficiency, and iron deficiency anaemia. Cannulation attempts caused bulla which progressed to ulceration. A pathergy phenomenon with high suspicion of pyoderma gangrenosum was postulated. Management with corticosteroids, cyclosporin, and finally ustekinumab, a novel biologic agent, yielded a beneficial response.

