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Radiation therapy for incompletely resected meningiomas.
Journal of Neurosurgery
|April 1, 1985
Summary
Postoperative radiation therapy for incompletely resected meningiomas is effective, with most patients showing no recurrence. This treatment offers prolonged progression-free intervals and minimal complications.
Area of Science:
- Neurosurgery
- Radiation Oncology
- Oncology
Background:
- Meningiomas are primary tumors of the central nervous system.
- Incomplete surgical resection of meningiomas can lead to recurrence.
- Postoperative radiation therapy is a treatment option for incompletely resected meningiomas.
Observation:
- Twelve patients with incompletely resected meningiomas received postoperative radiation therapy.
- Patients had a median follow-up of 54.5 months.
- Tumor progression was monitored using neurological exams and CT scans.
Findings:
- Nine out of twelve patients showed no evidence of recurrent meningioma after radiation therapy.
- Three patients experienced recurrences, two outside the radiation field and one within.
- Patients treated after prior recurrences had longer progression-free intervals compared to pre-radiation intervals.
Implications:
- Postoperative radiation therapy is a safe and effective adjuvant treatment for incompletely resected meningiomas.
- Radiation therapy can prolong progression-free survival in recurrent meningioma cases.
- Further research may explore optimal radiation fields to prevent marginal recurrences.