Optimization of Green Synthesis Formulation of Selenium Nanoparticles (SeNPs) Using Peach Tree Leaf Extract and...

Area of Science:

• Materials Science
• Nanotechnology
• Biotechnology

Background:

• Selenium nanoparticles (SeNPs) possess unique properties valuable across various industries.
• Conventional synthesis methods include microwave, bain-marie, autoclave, and heater techniques.

Purpose of the Study:

• To optimize SeNP synthesis for improved stability, concentration, particle size, and uniformity.
• To utilize central composite design for efficient formulation optimization.

Main Methods:

• Autoclave heating at 121°C and 1.5 bar for 15 minutes.
• Employing Prunus persica tree leaf extract as a reducing agent and Aloe Vera gel as a stabilizer.
• Assessing SeNP concentration, average particle size, zeta potential, and PDI using experimental design.

Main Results:

• The optimal SeNP formulation comprises 5.73 mL Prunus persica leaf extract, 13.45 mL sodium selenite solution, and 0.80 mL Aloe Vera gel.
• The optimized SeNPs demonstrated high stability, small average particle size, and favorable zeta potential.

Conclusions:

• Optimized SeNPs exhibit enhanced antioxidant and antifungal activities, suitable for diverse applications.
• Fine-tuning synthesis parameters is crucial for maximizing SeNP functional properties.