Cardiogenic shock in women: From risk factors to therapy

Area of Science:

• Cardiology
• Women's Cardiovascular Health

Background:

• Cardiogenic shock (CS) in women presents a significant cardiovascular challenge with high mortality rates.
• Non-ischemic causes, including stress-induced cardiomyopathy and peripartum cardiomyopathy, are prevalent in women, though acute myocardial infarction remains a critical consideration.

Purpose of the Study:

• To provide an overview of the etiology, risk factors, diagnosis, and treatment of cardiogenic shock specifically in women.
• To address the need for increased awareness and improved management strategies for CS in the female population.

Main Methods:

• Review of current literature and registry data on cardiogenic shock in women.
• Analysis of etiological factors, diagnostic approaches, and treatment modalities, including mechanical circulatory support.

Main Results:

• Women with CS are underrepresented in clinical trials and less likely to receive guideline-recommended therapies compared to men.
• Optimal management, particularly the role of mechanical circulatory support, requires further investigation in women.

Conclusions:

• There is a critical need for greater awareness and timely diagnosis of CS in women.
• Further research and robust data are essential to optimize the treatment and outcomes for women experiencing cardiogenic shock.