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Association between coffee and caffeine intake and functional dyspepsia.
Glareh Koochakpoor1, Asma Salari-Moghaddam2,3, Ammar Hassanzadeh Keshteli4,5
1Maragheh University of Medical Sciences, Maragheh, Iran.
Scientific Reports
|December 31, 2024
Summary
This study found no significant link between coffee or caffeine intake and functional dyspepsia (FD) in Iranian adults. Further research is needed in populations with higher coffee consumption.
Area of Science:
- Gastroenterology
- Nutritional Science
- Epidemiology
Background:
- Functional dyspepsia (FD) is a common gastrointestinal disorder.
- The relationship between coffee/caffeine intake and FD remains under-investigated.
Purpose of the Study:
- To examine the association between coffee and caffeine consumption and the odds of functional dyspepsia (FD) and its symptoms.
- To investigate this relationship in a large sample of Iranian adults.
Main Methods:
- A cross-sectional study involving 3362 adults (aged 18-55 years).
- Dietary intake assessed using a validated food frequency questionnaire (DS-FFQ).
- FD and its symptoms evaluated using a modified Persian version of the Rome III questionnaire; logistic regression used for analysis.
Main Results:
- The prevalence of FD was 14.5% in the study population.
- No significant association was found between coffee consumption (OR: 1.27) or caffeine intake (OR: 1.00) and the odds of FD.
- Coffee and caffeine intake were not significantly associated with FD symptoms like early satiation, post-prandial fullness, or epigastric pain, even when stratified by gender and BMI.
Conclusions:
- This study found no significant association between coffee or caffeine consumption and the odds of functional dyspepsia or its symptoms in Iranian adults.
- Further research is recommended in populations with higher coffee consumption to explore this relationship.
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