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Investigating the Spreading and Toxicity of Prion-like Proteins Using the Metazoan Model Organism C. elegans
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Topological confinement by a membrane anchor suppresses phase separation into protein aggregates: Implications for

Kalpshree Gogte1, Fatemeh Mamashli1, Maria Georgina Herrera2

  • 1Department Biochemistry of Neurodegenerative Diseases, Institute of Biochemistry and Pathobiochemistry, Ruhr University Bochum, Bochum 44801, Germany.

Proceedings of the National Academy of Sciences of the United States of America
|December 31, 2024
PubMed

Keywords:
liquid-liquid phase separationmembraneneurodegenerative diseasesprionprotein aggregation

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