Comparison of ocular biometry and refractive outcomes using two swept-source optical coherence tomography-based...

Area of Science:

• Ophthalmology
• Medical Devices
• Biometry

Background:

• Comparison of two swept-source optical coherence tomography (SS-OCT) biometers: Anterion and Argos.
• Evaluation of ocular biometry agreement and postoperative refractive outcome prediction.

Purpose of the Study:

• To assess the agreement in ocular biometry measurements between Anterion and Argos SS-OCT devices.
• To evaluate the prediction accuracy of postoperative refractive outcomes using these two biometers.

Main Methods:

• Ambispective analysis of 105 eyes undergoing cataract surgery.
• Biometric measurements (axial length, central corneal thickness, lens thickness, anterior chamber depth, corneal curvature) were taken using both Anterion and Argos.
• Intraocular lens (IOL) power, mean error (ME), and mean absolute error (MAE) were calculated using standard formulas (Barrett Universal II, Haigis, Hoffer Q).

Main Results:

• Anterion yielded significantly greater axial length, central corneal thickness, and lens thickness compared to Argos.
• Anterion showed smaller keratometry (corneal curvature) measurements than Argos; no significant difference in anterior chamber depth.
• Postoperative prediction errors varied by formula, with Anterion showing a slight myopic shift tendency; however, MAE and percentage of eyes within ±0.5D were not significantly different between devices.

Conclusions:

• Despite statistically significant differences in some ocular measurements (axial length, CCT, LT, K), these were not clinically significant.
• Both Anterion and Argos demonstrated comparable refractive predictability, with no significant differences in mean absolute error.
• Anterion showed a slight tendency towards myopic outcomes, but overall accuracy within ±0.5D was similar between the two SS-OCT biometers.