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Related Experiment Video

Updated: Apr 28, 2026

In situ Transverse Rectus Abdominis Myocutaneous Flap: A Rat Model of Myocutaneous Ischemia Reperfusion Injury
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Comparison of Patient-Reported Outcomes after Local Flap Coverage versus Amputation for Complex Lower Extremity

Neel Bhagat1, Connor Drake1, Steven Dawson1

  • 1Indiana University School of Medicine, Indianapolis, Indiana, United States.

Indian Journal of Plastic Surgery : Official Publication of the Association of Plastic Surgeons of India
|January 1, 2025
PubMed
Summary
This summary is machine-generated.

Fasciocutaneous flaps for lower extremity salvage yield better patient-reported outcomes (PROs) than amputation. Muscle flaps show similar PROs to amputation, indicating fasciocutaneous flaps may offer improved functional recovery and perceived health.

Keywords:
limb salvagelocal flaplower extremitypatient-reported outcomesquality of life

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Area of Science:

  • Orthopedic Surgery
  • Reconstructive Surgery
  • Patient-Reported Outcomes Research

Background:

  • Limited patient-reported outcomes (PROs) data exists for lower extremity salvage procedures.
  • Limb salvage is often achieved using local muscle or fasciocutaneous flaps.
  • Comparing PROs between flap types and amputation is crucial for treatment decisions.

Purpose of the Study:

  • To compare patient-reported outcomes (PROs) of lower extremity salvage using local fasciocutaneous flaps versus muscle flaps.
  • To compare PROs between limb salvage (fasciocutaneous or muscle flaps) and lower extremity amputation.
  • To evaluate functional recovery and perceived health status after different reconstructive procedures.

Main Methods:

  • A retrospective review of 61 patients undergoing lower extremity local flap reconstruction (n=33) or amputation (n=28) between 2014-2020.
  • Patient-reported outcomes were collected via telephone surveys using the Lower Extremity Functional Scale (LEFS) and SF-36.
  • Perioperative data was collected through chart reviews.

Main Results:

  • Fasciocutaneous flaps resulted in significantly higher LEFS and SF-36 physical and emotional functioning scores compared to amputation.
  • Muscle flaps showed significantly lower LEFS and SF-36 physical functioning scores compared to fasciocutaneous flaps.
  • Muscle flap patients reported similar LEFS and SF-36 scores to amputation patients.

Conclusions:

  • Local fasciocutaneous flaps for lower extremity salvage are associated with superior patient-perceived functional outcomes compared to amputation.
  • Muscle flaps for limb salvage yield comparable patient-reported outcomes to amputation, and are inferior to fasciocutaneous flaps.
  • Fasciocutaneous flaps may offer functional advantages, suggesting they could be a preferred option for limb salvage when feasible.