Clinical Radiologic Analysis of 2964 Papillary Breast Lesions

Background: Clinical management of papillary breast lesions (PBLs) remains controversial. Our objective was to analyze the independent risk factors associated with malignant PBLs. Methods: A retrospective review of clinical variables in 2964 patients with papillary lesions available for evaluation. Results: This retrospective study screened that older patients (≥ 50 years), postmenopausal, palpable tumor, tumor size ≥ 15 mm, peripheral tumor, and tumor with calcification were independent risk factors affecting malignant PBLs. Moreover, the probability of malignant PBLs without the appealed risk factors was only 3.4%. Conclusions: Patients without risk factors for papillary lesions can manage their health with imaging surveillance. The choice of surgical treatment for the remaining patients is a reasonable recommendation.