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Cardiac Action Potential

Cardiac Action Potential

Cardiac action potentials are essential for proper heart function, enabling the rhythmic contractions needed for adequate blood circulation. Nodal cells and Purkinje fibers, specialized for electrical conduction, generate these action potentials.
The cardiac action potential process involves a series of phases characterized by the movement of ions across the cardiac cell membranes, leading to the depolarization and repolarization of the cardiac myocytes.
Ionic Basis of Cardiac Action Potentials

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Programmed Electrical Stimulation in Mice

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Published on: May 26, 2010

Pre-excitation alternans in a cat.

L A Murphy¹, R K Nakamura²

¹University of Wisconsin-Madison School of Veterinary Medicine, 2015 Linden Drive, Madison, WI 53706, USA.

Journal of Veterinary Cardiology : the Official Journal of the European Society of Veterinary Cardiology

|January 1, 2025

Summary

This summary is machine-generated.

This study reports the first case of pre-excitation alternans in a cat with hypertrophic cardiomyopathy. The condition involved alternating ventricular pre-excited and sinus complexes on electrocardiogram.

Keywords:

Accessory pathway Feline Ventricular pre-excitation

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Area of Science:

Veterinary Cardiology
Feline Medicine
Cardiac Electrophysiology

Background:

Hypertrophic cardiomyopathy is a common cardiac disease in cats.
Ventricular tachycardia can be a serious complication of hypertrophic cardiomyopathy.
Electrocardiographic abnormalities are crucial for diagnosing cardiac conditions in felines.

Purpose of the Study:

To report the first case of ventricular pre-excitation alternans in a cat.
To describe the clinical presentation and diagnostic findings associated with this rare condition.
To contribute to the understanding of complex arrhythmias in feline hypertrophic cardiomyopathy.

Main Methods:

Referral of a nine-year-old domestic Shorthair cat presenting with vomiting, panting, and weakness.
Performance of an electrocardiogram (ECG) revealing concerning findings for ventricular tachycardia.
Echocardiography to diagnose hypertrophic cardiomyopathy and detailed ECG review for pre-excitation alternans.

Main Results:

Diagnosis of hypertrophic cardiomyopathy confirmed via echocardiogram.
ECG findings suggestive of ventricular pre-excitation alternans, with alternating pre-excited and sinus complexes.
Identification of a novel electrocardiographic pattern in a feline patient.

Conclusions:

Ventricular pre-excitation alternans is a newly described entity in feline cardiology.
This case highlights the importance of thorough ECG interpretation in cats with suspected arrhythmias and hypertrophic cardiomyopathy.
Further research is warranted to understand the prevalence and clinical significance of pre-excitation alternans in cats.