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Pre-excitation alternans in a cat
1University of Wisconsin-Madison School of Veterinary Medicine, 2015 Linden Drive, Madison, WI 53706, USA.
Summary
This study reports the first case of pre-excitation alternans in a cat with hypertrophic cardiomyopathy. The condition involved alternating ventricular pre-excited and sinus complexes on electrocardiogram.
Area of Science:
- Veterinary Cardiology
- Feline Medicine
- Cardiac Electrophysiology
Background:
- Hypertrophic cardiomyopathy is a common cardiac disease in cats.
- Ventricular tachycardia can be a serious complication of hypertrophic cardiomyopathy.
- Electrocardiographic abnormalities are crucial for diagnosing cardiac conditions in felines.
Purpose of the Study:
- To report the first case of ventricular pre-excitation alternans in a cat.
- To describe the clinical presentation and diagnostic findings associated with this rare condition.
- To contribute to the understanding of complex arrhythmias in feline hypertrophic cardiomyopathy.
Main Methods:
- Referral of a nine-year-old domestic Shorthair cat presenting with vomiting, panting, and weakness.
- Performance of an electrocardiogram (ECG) revealing concerning findings for ventricular tachycardia.
- Echocardiography to diagnose hypertrophic cardiomyopathy and detailed ECG review for pre-excitation alternans.
Main Results:
- Diagnosis of hypertrophic cardiomyopathy confirmed via echocardiogram.
- ECG findings suggestive of ventricular pre-excitation alternans, with alternating pre-excited and sinus complexes.
- Identification of a novel electrocardiographic pattern in a feline patient.
Conclusions:
- Ventricular pre-excitation alternans is a newly described entity in feline cardiology.
- This case highlights the importance of thorough ECG interpretation in cats with suspected arrhythmias and hypertrophic cardiomyopathy.
- Further research is warranted to understand the prevalence and clinical significance of pre-excitation alternans in cats.

