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Multiple intrahepatic artery aneurysms during the treatment for IgG4-related sclerosing cholangitis: A case report

Hotaka Tamura1, Yoshinori Ozono1, Keisuke Uchida1

  • 1Division of Gastroenterology and Hepatology, Department of Internal Medicine, Faculty of Medicine, University of Miyazaki, Miyazaki 889-1692, Japan.

World Journal of Hepatology
|January 2, 2025
PubMed

Insights

Multiple intrahepatic artery aneurysms can develop during treatment for IgG4-related sclerosing cholangitis (IgG4-SC). These aneurysms are a poor prognostic complication requiring prompt management.

Area of Science:

  • Vascular Surgery
  • Gastroenterology
  • Immunology

Background:

  • This case report details a patient with IgG4-related sclerosing cholangitis (IgG4-SC) undergoing treatment.
  • The patient was on maintenance therapy with prednisolone.

Observation:

  • A 64-year-old woman presented with abdominal pain and melena.
  • Imaging revealed multiple intrahepatic artery aneurysms during IgG4-SC treatment.
  • Emergency transarterial embolization was performed for the aneurysms.

Findings:

  • Transarterial embolization successfully treated the hepatic artery aneurysms.
  • Post-embolization, aneurysms resolved on imaging.
  • Anemia progression ceased and melena resolved, achieving hemostasis.

Implications:

  • Hepatic artery aneurysms are a significant complication of IgG4-SC.
  • Early recognition and intervention are crucial for managing these aneurysms.
  • This case highlights the importance of considering vascular complications in IgG4-SC patients.
Abstract

Keywords:
AtherosclerosisCase reportEmbolizationHepatic artery aneurysmIgG4-related sclerosing cholangitisMelenaPseudoaneurysm

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