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Brucella Endocarditis: A Case Series.

Sajad A Bhat1, Farooq A Guroo2, Ajaz N Koul2

  • 1Internal Medicine, Division of Infectious Diseases, Sher-I-Kashmir Institute Of Medical Sciences, Srinagar, IND.

Cureus
|January 2, 2025
PubMed
Summary
This summary is machine-generated.

Brucellosis can cause fatal cardiac endocarditis. Prolonged blood cultures and multispecialty care are crucial for diagnosing and managing this rare but severe zoonotic infection.

Keywords:
feverheart failurehuman brucellosisinfective endocarditisseptic embolic stroke

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Area of Science:

  • Infectious Diseases
  • Cardiology
  • Microbiology

Background:

  • Brucellosis is a prevalent zoonotic infection with potential for severe organ involvement.
  • Cardiac complications, particularly endocarditis, are rare but frequently fatal in Brucella infections.

Observation:

  • This case series details three patients with Brucella endocarditis presenting with diverse complications.
  • Brucella is a fastidious organism requiring specific culture techniques for accurate diagnosis.
  • Prolonged blood cultures (seven days) improved diagnostic yield.

Findings:

  • Infective endocarditis is the leading cause of mortality in patients with Brucella infection.
  • Management of complications like stroke necessitates a multidisciplinary approach.
  • Medical therapy alone led to favorable outcomes in two out of three patients.

Implications:

  • Highlights the importance of appropriate diagnostic methods for Brucella endocarditis.
  • Underscores the need for early surgical intervention when indicated for severe complications.
  • Emphasizes the role of prolonged culturing in identifying fastidious bacterial pathogens.