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Updated: Jul 11, 2026

Microscopy-based Assays for High-throughput Screening of Host Factors Involved in Brucella Infection of Hela Cells
Published on: August 5, 2016
Brucella Endocarditis: A Case Series
Sajad A Bhat1, Farooq A Guroo2, Ajaz N Koul2
1Internal Medicine, Division of Infectious Diseases, Sher-I-Kashmir Institute Of Medical Sciences, Srinagar, IND.
Abstract:
Brucellosis is one of the most common zoonotic infections present worldwide. It usually presents as a febrile illness but can affect multiple organs of the body. Although cardiac involvement in brucellosis is rare, it is a fatal organ involvement. The endocarditis is the most common cause of death among patients with Brucella infection. The management of complications of infective endocarditis like stroke requires a multispecialty approach. The Brucella being a fastidious organism requires proper culture technique for growth. The serological methods of diagnosis have limited value in areas with high seroprevalence of brucellosis. We present a case series of three patients who had Brucella endocarditis with varied complications and courses of illness. The practice of a prolonged culture of blood for seven days ensured growth on the culture medium. All three patients were managed with medical therapy only, with a favorable outcome in two patients. In this case series, we have highlighted the importance of proper diagnostic methods and early surgical intervention when indicated.
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