[Serum lipids and lipoproteins in peripheral vascular disease]

Serum lipids and lipoproteins were investigated in 102 cases with arteriosclerosis obliterans (ASO), 41 cases with Buerger's disease (TAO) and 133 normal controls. The following results were obtained. In ASO, triglyceride, beta-lipoprotein, free fatty acid were higher than control, but total cholesterol and lipid peroxide were not increased. LDL and VLDL increased though LCAT decreased in ASO. ASO had lower HDL-cholesterol, HDL-phospholipid and apoprotein-A levels than control. HDL-cholesterol/HDL-phospholipid and HDL-cholesterol/Apoprotein-A ratios decreased also, indicating changes in quality in addition to quantity. In young patients with ASO, total cholesterol and LDL were higher than in old one. The same tendency was found in patients with proximal occlusion (aorto-iliac). In TAO, triglyceride, free fatty acid and VLDL increased and HDL-cholesterol, Apoprotein-A and LCAT decreased than that of control. These data may suggest that the change of lipids and lipoproteins in ASO are same in coronary heart disease.