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Triboelectric Nanogenerator-Based Self-Powered Urinary Protein Detection Utilizing Triboelectric Material with
Qitao Zhou1, Wenxia Xu1, Liang Wang1
1State Key Laboratory of Biogeology and Environmental Geology, Engineering Research Center of Nano-Geomaterials of the Ministry of Education, Faculty of Materials Science and Chemistry, China University of Geosciences, Wuhan 430074, P. R. China.
ACS Nano
|January 2, 2025
Summary
A new sensing material and portable device enable convenient home monitoring of urinary protein for early chronic kidney disease (CKD) detection. This technology offers both qualitative and quantitative analysis, addressing limitations of current test strips.
Area of Science:
- Biomedical Engineering
- Materials Science
- Clinical Diagnostics
Background:
- Chronic kidney disease (CKD) is prevalent and can lead to renal failure if untreated.
- Home monitoring of urinary protein is crucial for early CKD detection.
- Existing test strips lack quantitative accuracy and are prone to contamination, hindering continuous monitoring.
Purpose of the Study:
- To develop a novel sensing material for dual qualitative and quantitative urinary protein detection.
- To create a portable, user-friendly device for home-based CKD screening.
- To overcome the limitations of current urinary protein test strips for chronic kidney disease (CKD) monitoring.
Main Methods:
- Development of a sensing material with colorimetric and triboelectric properties for urinary protein detection.
- Design of a multichannel portable device for stable energy input and environmental monitoring.
- Integration of the sensing material and device for simultaneous qualitative and quantitative analysis.
Main Results:
- Successful development of a sensing material enabling both colorimetric (qualitative) and triboelectric (quantitative) detection of urinary proteins.
- Creation of a portable device facilitating convenient and accurate home testing.
- Achieved naked-eye rapid qualitative detection and self-powered quantitative detection of urinary proteins.
Conclusions:
- The developed sensing material and portable device show significant potential for home-based urinary protein detection.
- This technology offers a promising solution for the early warning and management of chronic kidney disease (CKD).
- The system addresses the need for continuous, accurate, and accessible monitoring of urinary protein levels.
