Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Temperature and vascular stability in hemodialysis.

T Lindholm, H Thysell, Y Yamamoto

    Nephron
    |January 1, 1985
    PubMed
    Summary

    Lowering dialysis fluid temperature to 35°C improves vascular stability during hemodialysis. This study suggests adjusting dialyzer inlet temperature (TDi) to match blood temperature (TBa) prevents blood temperature fluctuations, enhancing patient safety.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The association of low-level air pollution with birth weight in a register-based study: potential effects below WHO AQ guidelines.

    BMC pregnancy and childbirth·2025
    Same author

    An observational analysis on the influence of parental allergic rhinitis, asthma and smoking on exhaled nitric oxide in offspring.

    Nitric oxide : biology and chemistry·2024
    Same author

    The burden of heat-related mortality attributable to recent human-induced climate change.

    Nature climate change·2021
    Same author

    IgE sensitization to food allergens and airborne allergens in relation to biomarkers of type 2 inflammation in asthma.

    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology·2018
    Same author

    The Interplay of Climate Change and Air Pollution on Health.

    Current environmental health reports·2017
    Same author

    Microbial characteristics in homes of asthmatic and non-asthmatic adults in the ECRHS cohort.

    Indoor air·2017

    Area of Science:

    • Nephrology
    • Cardiovascular Physiology

    Background:

    • Vascular instability is a common complication during hemodialysis.
    • Blood temperature in extracorporeal circuits may affect patient hemodynamics.

    Purpose of the Study:

    • To investigate the impact of dialyzer blood temperature on vascular stability in patients with pre-existing instability.
    • To determine optimal dialyzer blood temperature for minimizing hemodynamic changes during dialysis.

    Main Methods:

    • Continuous monitoring of mean arterial blood pressure and heart rate in 8 patients undergoing dialysis.
    • Adjusting the dialyzer blood inlet temperature (TDi) to achieve target blood return temperatures (TBv) of 37°C, 36°C, and 35°C.
    • Data collection over 4-hour dialysis sessions at each temperature setting.

    Related Experiment Videos

    Main Results:

    • Patients exhibited decreased mean arterial blood pressure and increased heart rate at TBv of 37°C and 36°C.
    • Vascular parameters remained relatively stable when TBv was maintained at 35°C.
    • Blood temperature returning from the extracorporeal circuit (TBa) was approximately 35.7°C at the start of dialysis.

    Conclusions:

    • The standard practice of using a 37°C dialyzer inlet temperature should be reconsidered.
    • Adjusting dialyzer temperature to match the patient's blood temperature (around 35.7°C) can mitigate vascular instability during hemodialysis.
    • Optimizing blood temperature management in extracorporeal circuits is crucial for patient safety and hemodynamic stability.