Identifying mild traumatic brain injury in the post-acute polytrauma setting: a scoping review of diagnostic

Matthew J Burke1,2, Yomna E Ahmed3, Zoe Li3

  • 1Hurvitz Brain Sciences Research Program, Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

Brain Injury
|January 3, 2025
PubMed
Abstract

Insights

Diagnosing mild traumatic brain injury (mTBI) in polytrauma patients is difficult due to overlapping symptoms and a lack of validated tools. Future research must prioritize developing effective screening methods for better patient outcomes.

Area of Science:

  • Neuroscience
  • Trauma Care
  • Diagnostic Medicine

Background:

  • Mild traumatic brain injury (mTBI) is often missed in polytrauma patients due to more severe injuries.
  • mTBI symptoms overlap with other conditions, complicating diagnosis in post-acute settings.
  • Currently, no validated diagnostic tools exist for mTBI in this population.

Purpose of the Study:

  • To conduct a scoping review of the literature on mTBI diagnosis in post-acute civilian polytrauma settings.
  • To identify existing diagnostic tools and assess their limitations.
  • To highlight the research gap in this critical area.

Main Methods:

  • Utilized the Arksey and O'Malley framework and PRISMA-ScR guidelines.
  • Focused on studies published between 2010 and 2024 concerning delayed mTBI diagnosis in adults.
  • Screened 696 identified studies, with only six meeting inclusion criteria.

Main Results:

  • Reviewed diagnostic tools including the Rivermead Post-Concussion Symptoms Questionnaire (RPQ), neuropsychological tests, advanced imaging, and oculomotor assessments.
  • Found existing tools have limited ability to confirm mTBI occurrence.
  • The American Congress of Rehabilitation Medicine's updated mTBI criteria show potential but require validation.

Conclusions:

  • A significant gap exists in validated diagnostic tools for mTBI in post-acute settings.
  • This diagnostic gap may negatively impact patient outcomes.
  • Prioritizing the development and validation of effective mTBI screening tools for post-acute polytrauma is crucial for future research.