Combination of Multi-Acid Superficial Peel and Hyaluronic Acid Boosting: A Novel Prejuvenation Strategy

Normal human life expectancy has increased; hence, growing interest in the field of skin quality is observed. Peels are common medical devices that stimulate new skin growth and improve texture. Injectable hyaluronic acid (HA)-based products act by replacing fragmented collagen. HA skin boosting is a new technique that is able to reduce aging indicators. The aim of this study was to evaluate the efficacy and safety of a multi-acid superficial peel combined with an HA skin booster to improve quality of the skin. We conducted a prospective study with patients presenting hyperpigmentation, skin dryness, loss of elasticity, or fine lines. The participants were required to apply either peel or booster treatment during an attack phase and during the followed maintenance phase. Subjective and objective evaluations were performed to assess clinical outcomes (i.e., skin hydration, firmness, and brightness). A total of 16 subjects participated in the study. We observed a higher satisfaction at the end of the treatment, compared to the baseline, for each of the three skin qualities (P < 0.0001). Similarly, analysis of physicians' global assessment scores demonstrated that physicians detected higher scores at the end of the study, compared to the baseline (P < 0.0001). Our study demonstrated the synergistic effect of a multi-acid superficial peel combined with HA skin boosting to improve skin appearance.