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Author Spotlight: Exploring the Role of Inflammation in the Co-occurrence of Primary Sjogren's Syndrome and Lung Adenocarcinoma
Published on: September 20, 2024
351
Primary Sjogren's Syndrome Presenting As Pleuritis and Pleural Effusion
Ashwin Varkey1, Kevin Shayani2, Viera Lakticova2
1Medicine, Lenox Hill Hospital, New York, USA.
Cureus
|January 3, 2025
Summary
Sjogren's syndrome, an autoimmune disease, rarely presents with pleural effusion. This case highlights Sjogren's pleuritis as an initial manifestation, emphasizing the need to consider extraglandular involvement.
Area of Science:
- Rheumatology
- Pulmonology
- Pathology
Background:
- Sjogren's syndrome is an autoimmune condition primarily affecting exocrine glands.
- Extraglandular involvement is rare, with pleural effusion being exceptionally uncommon.
Observation:
- A young woman presented with recurrent pneumonia, pleural effusion, and pulmonary embolism.
- She experienced pleuritic chest pain, dyspnea, and cough, leading to the discovery of a large left pleural effusion.
Findings:
- Infectious causes were excluded; pleural fluid analysis showed lymphocytic predominance.
- Biopsy confirmed autoimmune origin, specifically Sjogren's serositis.
Implications:
- This case underscores the importance of considering extraglandular manifestations of Sjogren's syndrome.
- Early diagnosis and treatment of Sjogren's pleuritis are crucial for managing unexplained pleural effusions in seropositive patients.
Keywords:
autoimmune disorderpleurisyrare cause of pleural effusionsjogrens syndromevideo-assisted thoracoscopic surgery (vats)More Related Videos
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